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September 2016 - July 1959




September 1, 2013, Vol 70, No. 9, Pages 890-989

In This Issue of JAMA Psychiatry


Abstract Full Text
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JAMA Psychiatry. 2013;70(9):890-891. doi:10.1001/jamapsychiatry.2013.2003

The Story of Glutamate in Drug Addiction and of N-Acetylcysteine as a Potential Pharmacotherapy

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JAMA Psychiatry. 2013;70(9):895-897. doi:10.1001/jamapsychiatry.2013.2207
Art and Images in Psychiatry

DepartureMax Beckmann

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JAMA Psychiatry. 2013;70(9):893-894. doi:10.1001/jamapsychiatry.2013.2005

Antipsychotic Medication During the Critical Period Following Remission From First-Episode PsychosisLess Is More

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JAMA Psychiatry. 2013;70(9):898-900. doi:10.1001/jamapsychiatry.2013.264

Maternal Smoking and Conduct Disorder in the Offspring

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JAMA Psychiatry. 2013;70(9):901-902. doi:10.1001/jamapsychiatry.2013.1951
Original Investigation

Brain Connectivity Abnormalities Predating the Onset of PsychosisCorrelation With the Effect of Medication

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JAMA Psychiatry. 2013;70(9):903-912. doi:10.1001/jamapsychiatry.2013.117

Schmidt and coauthors investigate whether dysfunctional brain connectivity during working memory predates the onset of psychosis and whether connectivity parameters are related to antipsychotic treatment.

Recovery in Remitted First-Episode Psychosis at 7 Years of Follow-up of an Early Dose Reduction/Discontinuation or Maintenance Treatment StrategyLong-term Follow-up of a 2-Year Randomized Clinical Trial

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JAMA Psychiatry. 2013;70(9):913-920. doi:10.1001/jamapsychiatry.2013.19

Wunderink et al conduct a long-term follow-up evaluation of a randomized clinical trial comparing maintenance treatment with dose reduction/discontinuation of antipsychotic drugs in patients with remitted first-episode psychosis. McGorry et al provide an editorial.

Converging Evidence for the Association of Functional Genetic Variation in the Serotonin Receptor 2a Gene With Prefrontal Function and Olanzapine Treatment

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JAMA Psychiatry. 2013;70(9):921-930. doi:10.1001/jamapsychiatry.2013.1378

Blasi et al examine the functional effects of the serotonin receptor 2a (5-HT2AR) gene on 5-HT2AR messenger RNA and protein expression, on prefrontal phenotypes linked with genetic risk for schizophrenia, and on treatment with olanzapine.

Comorbidities and Mortality in Bipolar DisorderA Swedish National Cohort Study

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JAMA Psychiatry. 2013;70(9):931-939. doi:10.1001/jamapsychiatry.2013.1394

Crump and coauthors examine the physical health effects of bipolar disorder using outpatient and inpatient data for a national population.

Psychotic Symptoms and Population Risk for Suicide AttemptA Prospective Cohort Study

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JAMA Psychiatry. 2013;70(9):940-948. doi:10.1001/jamapsychiatry.2013.140

Kelleher et al assessed psychotic symptoms (attenuated or frank) as a clinical marker of risk for suicide attempt.

Effectiveness of National Implementation of Prolonged Exposure Therapy in Veterans Affairs Care

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JAMA Psychiatry. 2013;70(9):949-955. doi:10.1001/jamapsychiatry.2013.36

Eftekhari et al evaluated the effectiveness of prolonged exposure therapy as implemented in a large number of veterans with posttraumatic stress disorder as part of ongoing efforts to transform care in a large health care system.

Maternal Smoking During Pregnancy and Offspring Conduct ProblemsEvidence From 3 Independent Genetically Sensitive Research Designs

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JAMA Psychiatry. 2013;70(9):956-963. doi:10.1001/jamapsychiatry.2013.127

Gaysina et al examine the relationship between maternal smoking during pregnancy and offspring conduct problems among children reared by genetically related and genetically unrelated mothers. Three studies using distinct but complementary research designs were used. Possible covariates were controlled for in the analyses. See the Editorial by Slotkin.

Atypical Developmental Patterns of Brain Chemistry in Children With Autism Spectrum Disorder

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JAMA Psychiatry. 2013;70(9):964-974. doi:10.1001/jamapsychiatry.2013.1388

Proton magnetic resonance spectroscopic imaging data were acquired longitudinally for children with autism spectrum disorder or developmental delay and primarily cross-sectionally for children with typical development by Corrigan and coauthors to examine cross-sectional and longitudinal patterns of brain chemical concentrations from 3 different age groups, beginning early in the clinical course.

Pervasive Rightward Asymmetry Shifts of Functional Networks in Autism Spectrum Disorder

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JAMA Psychiatry. 2013;70(9):975-982. doi:10.1001/jamapsychiatry.2013.382

Cardinale and colleagues examined the asymmetry of functional networks using a data-driven approach for a comprehensive investigation of hemispheric asymmetry in autism spectrum disorder (ASD).


Neuronal Network Plasticity and Recovery From Depression

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JAMA Psychiatry. 2013;70(9):983-989. doi:10.1001/jamapsychiatry.2013.1

Castrén describes the network hypothesis of antidepressant action that proposes that recovery from depression and related mood disorders is a gradual process that develops slowly and is facilitated by structured guidance and rehabilitation.

JAMA Psychiatry Masthead

JAMA Psychiatry

Abstract Full Text
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JAMA Psychiatry. 2013;70(9):892-892. doi:10.1001/jamapsychiatry.2013.2001