Rasetti and colleagues investigated whether altered brain responses, particularly in the hippocampus and parahippocampus, during the encoding phase of a simple declarative memory task were also observed in the unaffected siblings of patients with schizophrenia.
Hartz and colleagues compared substance use in individuals with severe psychotic illness with substance use in the general population.
In a methylome-wide association study, Aberg and coauthors identify schizophrenia DNA methylation biomarkers in the blood.
Bustillo et al examine glutamine, glutamate, and glutamine to glutamate ratio in the dorsal anterior cingulate, as well as their relationships with symptoms and cognition in schizophrenia.
Takayanagi et al examine the lifetime prevalence estimates of mental and physical disorders during midlife to late life using both retrospective and cumulative evaluations. Compton and Lopez provide commentary in a related editorial.
Allsop et al evaluate the safety and efficacy of nabiximols treating cannabis withdrawal with use of a 6-day regimen of nabiximols or placebo with standardized psychosocial interventions during a 9-day admission.
Maenner and colleagues aimed to assess potential effects of the DSM-5 autism spectrum disorder (ASD) criteria on ASD prevalence estimation by retrospectively applying the new criteria to population-based surveillance data collected for previous ASD prevalence estimation.
By linking population records for psychiatric disorders, McGrath et al determine the relative influence of maternal vs paternal age and older vs younger parents with respect to different mental health disorders in their offspring.
Ginsburg et al determine whether acute clinical improvement and treatment type (ie, cognitive behavioral therapy, sertraline, or their combination predicted remission of anxiety and improvement in global functioning at a mean of 6 years after randomization and examine predictors of outcomes at follow-up.
Chang et al estimate the association between attention-deficit hyperactivity disorder (ADHD) and the risk of serious transport accidents and explore the extent to which ADHD medication influences this risk among patients with ADHD.
Fazel and coauthors examine the relationship between traumatic brain injury and premature mortality and determine the role of psychiatric comorbidity.