Although fungous infection of the brain is not a medical curiosity, it is sufficiently unusual to warrant the putting on record of even a small number of cases, such as the 4 reported here.
Several collective studies are on record, one of the most important of which is the review by Boyd and Crutchfield1 in 1921. In 1928 Jacobson2 reported 4 cases, in 1 of which there was cerebral involvement, and set the number of recorded cases at that time at 92. In 1936 the California state department of health3 reported 450 cases, most of which had occurred in California, with 224 deaths. The number of cerebral complications in these cases was not mentioned, but Beck,4 in a review of 286 cases occurring in California up to 1931, had found intracranial lesions in 18. Courville and Abbott,5 who in 1938 reviewed the cases in the
ANDERSON GC. FUNGOUS INFECTIONS OF THE BRAINREPORT OF FOUR CASES. Arch Surg. 1941;42(2):379-385. doi:10.1001/archsurg.1941.01210080179010