Symptomatic compression of the central nervous system secondary to the use of Gelfoam (absorable gelatin sponge) in a closed space occurred in two cases. Absorbable gelatin sponge may be used to control bleeding; but it should be removed from closed spaces where vital tissues may be compressed against rigid walls by fluid accumulation.
Herndon JH, Grillo HC, Riseborough EJ, Rich JC. Compression of the Brain and Spinal Cord Following Use of Gelfoam. Arch Surg. 1972;104(1):107. doi:10.1001/archsurg.1972.04180010101027