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Invited Commentary
December 2014

Examining the Cost-effectiveness of 2-Level Cervical Total Disc Replacement

Author Affiliations
  • 1Department of Neurosurgery, University of Michigan, Ann Arbor
JAMA Surg. 2014;149(12):1239. doi:10.1001/jamasurg.2014.721

Cervical total disc replacement was developed to treat symptoms associated with disc degeneration while preserving physiological motion. Several clinical trials have compared its use with traditional anterior cervical discectomy and fusion for both single-level and multilevel disease.1,2 Ament et al3 analyzed data from a published multicenter randomized clinical trial by Davis et al4 that demonstrated the clinical superiority of the Mobi-C cervical artificial disc vs anterior discectomy and fusion for 2-level contiguous degenerative disc disease and proposed that 2-level total cervical disc replacement is a cost-effective intervention.

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