Drs Gosling et al have brought to our attention their use of urine microalbumin excretion for the early identification of patients at risk for developing pulmonary dysfunction or adult respiratory distress syndrome after injury or surgery. They suggest that such early identification may better define patients for trials of anti-inflammatory agents. I agree with them that this could be helpful, particularly if we could prospectively prevent the "clinically significant capillary leak syndrome."
Baue AE. Systemic Inflammatory Response Syndrome and Magic Bullets: Finding the Target and Improving the Aim—Reply. Arch Surg. 1998;133(3):334-335. doi: