Although the causal relationship between SJW and the lowering of cyclosporine levels has been well documented and the potential loss of allograft owing to rejection is real, several points of discussion arise:
The transplant community (health care personnel as well as transplant patients) needs to be aware of this important report.
Cao S. St John's Wort Supplements Endanger the Success of Organ Transplantation—Invited Critique. Arch Surg. 2002;137(3):319. doi:10.1001/archsurg.137.3.319