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Amri and colleagues1 have provided a retrospective review on the effect of margin positivity on survival among patients with colon cancer. They have found that, although rare, radial margin positivity is associated with a higher recurrence rate, an increased risk of death, and a shorter survival. At first, the concept seems foreign. Generally, it is rare that a colon cancer should have a positive radial margin (unlike rectal cancer, in which the resection margins are limited by bony structures) because most structures adjacent to the colon are resectable. However, in this study,1 a radial positive margin was shown to be an independent predictor of survival.
Efron J. The Role of the Radial MarginFurther Call for Standardization of Colon Cancer Care. JAMA Surg. 2015;150(9):898. doi:10.1001/jamasurg.2015.1549