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Research Letter
October 2016

Implementation of an Infection Prevention Bundle to Reduce Surgical Site Infections and Cost Following Spine Surgery

Author Affiliations
  • 1Cleveland Clinic Lerner College of Medicine, Cleveland, Ohio
  • 2Cleveland Clinic Center for Spine Health, Cleveland Clinic, Cleveland, Ohio
  • 3Department of Neurological Surgery, Cleveland Clinic, Cleveland, Ohio
  • 4Department of Neurological Surgery, Johns Hopkins Medicine, Baltimore, Maryland
JAMA Surg. 2016;151(10):988-990. doi:10.1001/jamasurg.2016.1794

An estimated 158 000 surgical site infections (SSIs) occur in the Unites States annually, at a cost of $3.45 billion to $10.07 billion.1,2 Investigations have demonstrated the efficacy of infection prevention bundles in reducing SSIs across multiple surgical specialties.3,4 Neurosurgical SSIs incur the highest costs, and spine surgeries account for more than 1.01 million procedures annually, presenting an opportunity for reducing health care–related harm and expenditures.5 We hypothesized that implementation of an infection prevention bundle would be associated with a reduction in SSIs and disease-specific costs.

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