[Skip to Content]
[Skip to Content Landing]
Views 416
Citations 0
Invited Commentary
November 2016

Acute Cholangitis ManagementPrevention of Organ Failure and Death

Author Affiliations
  • 1Department of Surgery, John A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu
JAMA Surg. 2016;151(11):1045. doi:10.1001/jamasurg.2016.2351

The article by Schwed et al1 compared a more recent cohort of patients with acute cholangitis (AC) at 1 of the 2 institutions (validation cohort) with a historical group of similar patients (derivation cohort). Their prior study of the derivation cohort identified 3 independent admission risk factors that predisposed to adverse outcomes in AC: white blood cell (WBC) count greater than 20 000 cells/µL (to convert to ×109 per liter, multiply by 0.001), total bilirubin level greater than 10 mg/dL (to convert to micromoles per liter, multiply by 17.104), and advanced age.2 The aim of the current study was to validate the criteria previously identified.

First Page Preview View Large
First page PDF preview
First page PDF preview
×