Acute appendicitis and acute cholecystitis, if left untreated, can lead to pregnancy loss in as many as 23% of cases.1,2 High-quality data have been lacking to help inform the optimal management of acute appendicitis and acute cholecystitis in pregnant patients along with management of risk factors and complications related to the pregnancy. To date, studies evaluating this topic have focused largely on the timing of surgery related to the pregnancy term, with most studies indicating the second trimester as the safest in an elective or semi-elective surgery scenario.
Massoumi RL, Hines OJ. Changing Outcomes in Pregnant Surgical Patients. JAMA Surg. Published online January 18, 2017. doi:10.1001/jamasurg.2016.5046