In Reply Ruan and colleagues raise several important issues regarding our recent research letter,1 namely the definition of persistent postoperative opioid use, the extent to which these results differ from the related literature,2- 4 and the potential for patients having received opioid prescriptions from health care professionals other than their surgeons.
Soneji N, Clarke HA, Wijeysundera DN. Persistent Opioid Use After Major Surgery—Reply. JAMA Surg. Published online February 01, 2017. doi:10.1001/jamasurg.2016.5656