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JAMA Surgery Clinical Challenge
July 12, 2017

A Young Woman With a New Breast Mass

Author Affiliations
  • 1Breast Imaging–Radiological Department, Aziende USL Toscana NordOvest, Carrara, Italy
  • 2University of Pisa, Pisa, Italy
  • 3Pathology Department, Aziende USL Toscana NordOvest, Carrara, Italy
JAMA Surg. Published online July 12, 2017. doi:10.1001/jamasurg.2017.2172

A 28-year-old woman visited the emergency department for a sudden, diffuse, and painful enlargement of the upper quadrants of the left breast with edema and palpable axillary lymph nodes without clinical signs of inflammation or infection (Figure 1A). She had neither fever nor skin redness but was experiencing fatigue.

The patient had stopped breastfeeding 10 months before the emergency department admission, and she had a recent history of pneumonia self-medicated with antibiotics. She had no family history of breast or ovarian cancer and no history of drug addiction or hyaluronic acid or free silicone injections in the breast. She denied any trauma to the breast.

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