Citations 0
Correspondence and Brief Communications
September 2001

Endothelin Plasma Levels in Burn Patients

Author Affiliations

Copyright 2001 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.2001

Arch Surg. 2001;136(9):1084. doi:

For nearly a decade, the fundamental questions of my laboratory have been, "Is endothelin an alternate activating pathway for leukocytes in injury, ischemia, and sepsis?" and "Is monocyte/macrophage-produced endothelin a clinically relevant factor in the vasoconstriction observed in some vascular beds with injury and infection?" Because the motto of my lab is "If we knew what we were doing, we wouldn't call it research," I must confess that after 10 years of investigating and thinking about these questions, I still do not know the answer to either of them.

First Page Preview View Large
First page PDF preview
First page PDF preview