Surgical oncology in the 20th century centered on the resection of primary cancers and local recurrences. In the 21st century, that tradition may well change to center on the resection of metastatic disease. Metastasis from STS to the lungs has been one of the main sites of disease for this new direction. Much information has been gathered over the last few decades to delineate the appropriate patients with metastatic disease who would benefit from resection. For patients to benefit, the procedures must have acceptable morbidity and mortality and long-term survival must show improvement over other methods. The effect on long-term survival of resection of metastatic disease has not been studied in a randomized fashion. Information has been gathered from several large retrospective studies.
Kemeny MM. Benefit of Surgical Treatment of Lung Metastasis in Soft Tissue Sarcoma—Invited Critique. Arch Surg. 2007;142(1):76. doi:10.1001/archsurg.142.1.76