[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Citations 0
Correspondence and Brief Communications
June 1, 2007

Are Single-Dose Preoperative Antibiotic Regimens Really Appropriate?—Reply

Arch Surg. 2007;142(6):577. doi:10.1001/archsurg.142.6.577-a

In reply

We read with interest the comments by Dr Schmidt and feel that there are some points to consider. Our study was not aimed to prove that 1-dose prophylaxis is as effective as a 24-hour regimen. In fact, the objectives of this study were to demonstrate how to implement a 1-dose regimen in a general hospital. The fact that 1-dose prophylaxis reduces surgical site infections as effectively as a 24-hour regimen had already been demonstrated in innumerous trials, such as the one published by Scher.1 One-dose prophylaxis is a widely approved recommendation published in several guidelines,2 some of them cited in our article.

First Page Preview View Large
First page PDF preview
First page PDF preview