Ng and colleagues have demonstrated that OLT can be safely performed for salvage in patients with recurrent HCC. The study group consisted of 60 patients who developed recurrent intrahepatic HCC after primary hepatic resection. Of the 60 patients, 12 underwent salvage OLT and 48 underwent various nontransplant therapies. These therapies included hepatic re-resection, TACE, and PEI. In comparing overall survival between the 2 treatment options, the authors found no difference between salvage transplant and nontransplant therapies for patients with recurrent HCC.
Brems JJ. Survival Analysis of Patients With Transplantable Recurrent Hepatocellular Carcinoma—Invited Critique. Arch Surg. 2008;143(1):74. doi:10.1001/archsurg.2007.16