This 2-year study by Misteli and colleagues relates SSI to the incidence of surgical glove perforation in more than 4100 general surgery patients. Glove perforation occurred in 16.3% of cases and rose dramatically in cases lasting longer than 2 hours (34.0% vs 9.4%). Surgical site infection was identified in 7.5% of the cases in which there was a glove perforation vs 3.9% when there was none. The essence of the study resides in the multivariate logistic regression analysis, by which glove perforation was found to be a significant risk factor for SSI but only in cases in which prophylactic antibiotics were not used.
Cornwell EE. Surgical Glove Perforation and the Risk of Surgical Site Infection—Invited Critique. Arch Surg. 2009;144(6):558. doi:10.1001/archsurg.2009.71