Resection remains the cornerstone of curative treatment for gastric cancer, but it is associated with a cure rate of 25% to 35%. Recent positive results from large phase 3 trials1- 3 leave the surgical oncologist with several options. Two accepted standards of care in the West focus on adjuvant CT-RT based on the North American Intergroup 0116 trial and perioperative CT based on the MAGIC trial from Britain.
Ferri L, Mulder DS. Further Refinement of the Optimal Treatment Following Radical Gastric Resection for Gastric AdenocarcinomaComment on “Adjuvant Chemoradiotherapy in Patients With Stage III or IV Radically Resected Gastric Cancer”. Arch Surg. 2010;145(3):239. doi:10.1001/archsurg.2010.3