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August 2010

ERCP or Laparoscopic Exploration for the Treatment of Suspected Choledocholithiasis?

Author Affiliations

Authors Affiliations: Department of Medicine and Division of Gastroenterology and Hepatology, Johns Hopkins Medical Institutions, Baltimore, Maryland.

Arch Surg. 2010;145(8):796. doi:10.1001/archsurg.2010.128

We read with interest the study by Rogers et al comparing ERCP/S + LC with LC + LCBDE for the treatment of cholelithiasis and choledocholithiasis.1 We would like to offer a few comments on this study.

While the primary outcome of the study was bile duct stone clearance, the sample size was not calculated a priori. Although a nonsignificant bile duct stone clearance rate difference of 10% was seen between the ERCP and LCBDE arms of the study, the study could have been underpowered to detect a significant difference.

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