We read with interest the study by Rogers et al comparing ERCP/S + LC with LC + LCBDE for the treatment of cholelithiasis and choledocholithiasis.1 We would like to offer a few comments on this study.
While the primary outcome of the study was bile duct stone clearance, the sample size was not calculated a priori. Although a nonsignificant bile duct stone clearance rate difference of 10% was seen between the ERCP and LCBDE arms of the study, the study could have been underpowered to detect a significant difference.
Singh VK, Khashab MA, Okolo PI, Kalloo AN. ERCP or Laparoscopic Exploration for the Treatment of Suspected Choledocholithiasis?. Arch Surg. 2010;145(8):796. doi:10.1001/archsurg.2010.128