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August 2010

Association With a High Number of Lymph Nodes and Microsatellite Instability in Colorectal Cancer—Reply

Author Affiliations

Author Affiliations: D[[eacute]]partement Medico-Chirurgical de Pathologie Digestive (Drs Eveno, Valleur, and Pocard), and D[[eacute]]partement d[[rsquo]]Anatomopathologie (Dr Nemeth), Assistance Publique des H[[ocirc]]pitaux de Paris, H[[ocirc]]pital Lariboisi[[egrave]]re, and Centre National de la Recherche Scientifique Unit[[eacute]], Mixte de Recherche 7151, H[[ocirc]]pital St Louis (Drs Soliman and de The), Universit[[eacute]] Paris 7, and Institut National de la Sant[[eacute]] et de la Recherche M[[eacute]]dicale, Unit[[eacute]] Mixte de Recherche S762, Instabilit[[eacute]] des Microsatellites et Cancers, Universit[[eacute]] Pierre et Marie Curie[[ndash]]Paris 6 (Dr Praz), Paris, France; and Academic Department of Pathology, Cancer Research[[ndash]]United Kingdom Colorectal Cancer Unit, St Mark's Hospital, Harrow, London, England (Dr Talbot).

Arch Surg. 2010;145(8):799-800. doi:10.1001/archsurg.2010.147

In reply

We thank Kjetil Søreide and coauthors for their interesting comments. It is important to confirm our results, as they are reported in another recent publication, using another statistical analysis. Whatever the analysis, the association between a particular tumor pathway, MSI, and a specific number of isolated lymph nodes are of major interest as outlined by Berho and Wexner.1

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