Simple, nonspecific ulcer is a pathologic lesion which occurs in the colon. It may exist as a single lesion or it may be multiple. The fact that it does occur and usually tends to perforate should make one ever mindful of its occurrence.
By simple ulcer is meant an ulcerating lesion which is not due to the action of any specific organism such as the specific ulcer of tuberculosis, syphilis, ulcerative colitis, dysentery, typhoid fever or to the local action of any chemical agent, and which is not secondary or above a malignant tumor causing constriction.
This series comprises fifty-three cases; fifty were collected from the literature and three are cases that I observed. In this series, the cases include simple ulcers of the colon regardless of their location. Both perforated ulcers and chronic latent ulcers have been considered, since in certain patients the ulcers may have been multiple, one
BARRON ME. SIMPLE, NONSPECIFIC ULCER OF THE COLON. Arch Surg. 1928;17(3):355-407. doi:10.1001/archsurg.1928.01140090002001