In generalized amyloidosis, deposits are not uncommonly found in the vessels of the thyroid as well as in other organs, but the quantity is rarely sufficient to produce enlargement of the gland or in any other way to give evidence of its presence during life. Little mention is made in the literature of amyloid goiter or localized amyloidosis of the thyroid without demonstrable deposits elsewhere. The rarity of the condition together with its interesting clinical and pathologic manifestations warrant the recording of further instances.
REPORT OF A CASE
—Mr. H. N., aged 54, entered St. Vincent's Hospital on the service of Dr. T. M. Joyce on March 3, 1929. The patient had noticed an enlargement of his thyroid gland for two years before admission, but no symptoms had developed until the last three months. At the time of entry, these consisted of dysphagia, dyspnea on exertion and an uncomfortable
HUNTER WC, SEABROOK DB. GOITROUS ENLARGEMENT OF THE THYROID GLAND DUE TO AMYLOIDOSIS. Arch Surg. 1930;20(5):762-766. doi:10.1001/archsurg.1930.01150110051003