Rational management of surgical wounds demands that the surgeon possess accurate knowledge of the processes of repair in tissues in human beings. The knowledge of healing of wounds in human beings is drawn largely by analogy from the observations of wounds in laboratory animals. Since the processes observed in wounds in human beings differ from those observed in tissues of animals, it is necessary to review the process of healing as found in the former.
In the first study, it was observed that there are two distinct types of healing processes, an epithelial and a fibrous process. Epithelial healing has been described. This paper deals with the fibrous type which is common to the dermis, fat, fascia and muscle. The observations and conclusions made are of direct clinical value.
STUDY OF CELLULAR MECHANICS IN FIBROUS HEALING
The material for this work consists of complete, transverse sections of surgical wounds in
HARTWELL SW. SURGICAL WOUNDS IN HUMAN BEINGSA HISTOLOGIC STUDY OF HEALING WITH PRACTICAL APPLICATIONS: II. FIBROUS HEALING. Arch Surg. 1930;21(1):76–96. doi:10.1001/archsurg.1930.01150130079004