Advances in the diagnosis and treatment of a disease entity are dependent on a knowledge of all the available data both from a clinical and from a pathologic point of view and from the results obtained by the various modes of therapy.
In the following study, an attempt will be made to correlate the various clinical features with the pathologic process involved, and to throw some light on the rather obscure results that have hitherto obtained in the treatment for metastases of the bone.
For purposes of analysis, it has been found convenient to group the 334 cases of bony metastases according to the primary tumor from which the dissemination occurred, thus emphasizing the entire clinical picture of each type of secondary neoplastic deposit, and, so far as possible, to determine accurately the process of histogenesis and the variations in response to treatment.
CARCINOMA OF THE BREAST
Carcinoma of the
COPELAND MM. SKELETAL METASTASES ARISING FROM CARCINOMA AND FROM SARCOMA. Arch Surg. 1931;23(4):581-654. doi:10.1001/archsurg.1931.01160100040003