As the result of a preliminary study of the value of sodium amytal as an anesthetic in general surgery, I am of the opinion that its best field of usefulness is as a basal anesthetic administered intravenously. In this regard I am quite in accord with the views of Holman and Palmer1 and others, and I now prefer to use comparatively small doses of the drug, supplementing it with some form of inhalation anesthetic, either nitrous oxide and oxygen or ether, preferably the former.
My experience with sodium amytal by mouth has been comparatively small, and no accurate comparison of the cases in which it was so given could be made with the present series. It has been my observation, however, that the results have been considerably less satisfactory and the effect less certain with such a method of administration. The intravenous route enables one to gage accurately the
RANSOM HK. INTRAVENOUS SODIUM AMYTAL AS AN ADJUNCT IN ANESTHESIA. Arch Surg. 1932;24(6):1044-1051. doi:10.1001/archsurg.1932.01160180154008