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December 1933


Author Affiliations

From the Cleveland Clinic.

Arch Surg. 1933;27(6):1087-1108. doi:10.1001/archsurg.1933.01170120111005

Since the first case reported by Hamberger1 in 1746, the rarity of primary duodenal malignancy has been so stressed that rarely do textbooks mention it, clinicians consider it or surgeons encounter it with a thorough knowledge of the best methods to adopt when this condition unexpectedly presents itself at laparotomy. Therefore, the purposes of this paper are to present a rather thorough summary of the literature on the subject, to emphasize the consideration of a primary malignant disease of the duodenum in the differential diagnosis of lesions of the upper part of the abdomen, to outline the various methods of treating patients with this disease and to add 2 cases to the few that have been reported.

INCIDENCE  In order that the rarity of primary carcinoma of the duodenum be better appreciated, it might be well to consider first the incidence of intestinal and small intestinal carcinoma as shown

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