During a survey of the use of avertin in the general surgical service since 1930, certain points were noted which when correlated with known reactions to avertin were deemed of sufficient interest to merit publication. The number of cases in which avertin was used and their general distribution as to types of surgical procedures are considered sufficient to permit a comparison of the influence of age and sex on the response to a range of doses, as well as of the adaptability of this substance for different types of surgical procedures and for use with different supplementary anesthetics. This report also permits a direct comparison of the relative premedication values of two entirely different types of hypnotics, i. e., avertin (tribromethyl alcohol) and pentobarbital sodium (sodium ethyl [1-methyl-butyl] malonyl urea) used for similar purposes in the same surgical service. The report on pentobarbital sodium will appear separately.
The age range
BARLOW OW, FIFE GL, HODGINS AC. AVERTIN IN PREANESTHETIC MEDICATIONA SURVEY OF 1,831 SURGICAL ANESTHESIAS. Arch Surg. 1934;29(5):810-827. doi:10.1001/archsurg.1934.01180050115011