Tumors Among Dye Workers.
—Anderson24 stated that occupation is a causal factor in the development of vesical tumors among workers in aniline dyes. The duration of occupation and not the age of the patient is the determining factor in the development of such tumors. The familial history is apparently an unimportant factor. Neither positive nor negative symptoms and signs are conclusive evidence of the presence or absence of vesical tumors among these persons. A positive diagnosis of such a tumor can be made only by early and periodic cystoscopic examinations.Gehrmann25 stated that vesical tumors occur more commonly among dye workers than in other persons and that in his experience such tumors occurred among 4.5 per cent of the former. The combined experiences of the dyeing industries of Germany, Switzerland, England and America indicate that aniline, alpha and beta naphthylamine and benzidine probably are the etiologic compounds.
SCHOLL AJ, JUDD ES, VERBRUGGE J, HEPLER AB, GUTIERREZ R, O'CONOR VJ. A REVIEW OF UROLOGIC SURGERY. Arch Surg. 1934;29(5):866–894. doi:10.1001/archsurg.1934.01180050171015