It has now become generally understood that the treatment of peptic ulcer consists of a thorough medical regimen before an operation is considered. For that reason physicians are now encountering complications from prolonged medical management as well as those which result from improper selection of patients that need to be operated on.
It seems better not to differentiate between gastric and duodenal lesions on the ground of malignant transformation. The etiology is apparently the same for both gastric and duodenal lesions, and the symptoms are essentially the same. Most clinicians that have had the opportunity to observe the clinical course of gastric neoplasm and of gastric ulcer under medical management feel definitely that malignant transformation in gastric ulcer is rare. For that reason one need not be concerned with a different method of treatment of gastric and of duodenal ulcer to prevent malignant changes. Certainly, experience in the clinic for
HINTON JW. SEQUELAE OF PEPTIC ULCER FOLLOWING MEDICAL AND SURGICAL TREATMENT. Arch Surg. 1935;31(1):137-150. doi:10.1001/archsurg.1935.01180130140008