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Article
August 1935

PEPTIC ULCER FOLLOWING EXPERIMENTAL JEJUNOCOLOSTOMY

Author Affiliations

LOS ANGELES
From the Department of Surgery of the University of Chicago.

Arch Surg. 1935;31(2):241-252. doi:10.1001/archsurg.1935.01180140069005
Abstract

An unexpected and high incidence of "spontaneous" gastric and duodenal ulceration following jejunocolostomy, which was done for studies other than of peptic ulcer, led to an investigation of this unusual and interesting phenomenon, a preliminary report of which has been made.1

Numerous methods have been devised whereby acute, subacute and chronic ulceration of the stomach and duodenum can be produced experimentally. Many important observations on the etiology and pathogenesis of peptic ulcer have been made as a result of experimentation on animals. However, I agree with Ivy and Fauley,2 who stated that there is still much to be learned about this complex problem. The literature on this subject is far too voluminous to summarize in this article. Among some of the more important articles, in which complete bibliographies dealing with this question may be found, are those written by Mann and Williamson,3 McCann,4 Ivy and Fauley,

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