The ultimate results of radical operation on the pancreas and ampulla of Vater have not been as successful as one would desire because of several factors, the chief of which are: (1) the insidious onset of disease; (2) the poor condition of the patients; (3) the relative inaccessibility of the lesions; (4) the proximity of important structures which cannot be sacrificed, and (5) technical difficulties. Thus there has been a great tendency to treat such lesions in a more conservative manner. This being the case, it seemed of interest to compare the results obtained from the radical procedures with those following purely palliative operations in order to ascertain whether one is justified in attempting complete removal of the diseased tissue.
This study is based on 179 cases, in 158 of which the lesion originated in the head of the pancreas; in the remaining 21 it originated in the ampulla of
JUDD ES, HOERNER MT. SURGICAL TREATMENT OF CARCINOMA OF THE HEAD OF THE PANCREAS AND OF THE AMPULLA OF VATER. Arch Surg. 1935;31(6):937-942. doi:10.1001/archsurg.1935.01180180089004