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Article
April 1936

DISTURBANCES IN GASTRO-INTESTINAL FUNCTION AFTER LOCALIZED ABLATIONS OF CEREBRAL CORTEX

Author Affiliations

JAMES SPINDLER; AUGUSTA, GA.
From the Department of Anatomy, University of Georgia College of Medicine.

Arch Surg. 1936;32(4):618-623. doi:10.1001/archsurg.1936.01180220044003
Abstract

The great difficulty of keeping the totally decorticated animal in a state of suitable nutrition led us to suspect an intrinsic derangement of digestion. It was observed that operations on the frontal lobe were followed by an especially high mortality rate occurring during the third and fourth postoperative weeks. Observation of the function of the stomachs of such animals by previously made fistulas appeared to point to a disturbance of gastric motility. A thorough study of a "chronic" decorticated dog pointed toward evidence of deranged autonomic function. The present series of observations represents an attempt to investigate the phenomena of gastric motility after injury to cortical tissue of the frontal lobe by the use of the Cannon technic of direct visualization with the fluoroscope.

MATERIAL AND METHODS  Because of the carefully estimated normal standards of Cannon the cat was chosen as the experimental animal. After a variable period of preliminary

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