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Article
September 1936

EFFECT OF FAT INTRODUCED INTO THE JEJUNUM BY FISTULA ON MOTILITY AND EMPTYING TIME OF THE STOMACH

Author Affiliations

ROCHESTER, MINN.
From the Division of Experimental Medicine, the Mayo Foundation.

Arch Surg. 1936;33(3):451-466. doi:10.1001/archsurg.1936.01190030104005
Abstract

Although considerable experimental work has been done in the last decade on the question of inhibition of gastric motility by fat, with very suggestive results, little of this research has made use of the barium sulfate meal and fluoroscope. Because this method offers the best approach to normal conditions, with no disturbance of the nervous or muscular continuity of the stomach, it appears to be a logical means by which to observe this phenomenon of inhibition. Accordingly, making use of the barium sulfate meal and fluoroscope and with dogs as subjects, I undertook the study now reported. Since the upper portion of the small intestine is believed to be the site of formation of the inhibitory agent, I studied the effect produced on the emptying of a barium sulfate meal from the stomach by fat introduced into the jejunum by way of a fistula. The influence of various control substances

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