Circulatory disturbances resulting from either experimentally produced venous stasis or obstruction of the arterial blood supply have been claimed to produce the changes of chronic arthritis. If venous stasis or passive congestion is capable of producing chronic arthritis, then the joints of the ankles and feet of persons with long-standing edema and stasis from varicose veins of the legs should show evidence of arthritis. In an effort to determine what effect if any venous stasis has clinically on the production of chronic arthritis, thirty cases of varicose veins of long standing in which definite and prolonged edema of the ankles and feet had existed were studied.
The patients in this group of cases presented histories of longstanding varicose veins of the legs with marked congestion of the ankles and feet associated with edema, cyanosis and occasionally eczematous changes of the skin, such as scaling and brownish discolorations. A palpable decrease
McMASTER PE. INFLUENCE OF VENOUS STASIS ON THE PRODUCTION OF CHRONIC ARTHRITIS. Arch Surg. 1937;35(5):833-840. doi:10.1001/archsurg.1937.01190170002001