A malignant tumor of Meckel's diverticulum is rare enough to be considered a pathologic curiosity. The literature on other lesions associated with Meckel's diverticulum, however, is increasing each year. We have therefore thought it opportune to combine the report of a case of a malignant tumor of Meckel's diverticulum with a general survey of the literature.
Meckel's diverticulum is a developmental anomaly of the intestinal tract which is found in about 2 per cent of all adults. The mechanism responsible for the production of this anomaly, as is well known, is failure of the omphalomesenteric duct and its accompanying vessels to become completely obliterated. Normally this obliteration takes place in the third to the fifth week of embryonic life. The yolk stalk may fail to become completely obliterated, leading in rare cases to an intestinal fistula opening through the umbilicus; occasionally the duct becomes obliterated, except at its distal part.
NYGAARD KK, WALTERS W. MALIGNANT TUMORS OF MECKEL'S DIVERTICULUMREPORT OF A CASE OF LEIOMYOSARCOMA. Arch Surg. 1937;35(6):1159–1172. doi:10.1001/archsurg.1937.01190180131010