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Article
March 1938

EFFECT OF HYPOPROTEINEMIA ON WOUND DISRUPTION

Author Affiliations

PHILADELPHIA
Elily Fellow in Surgical Research.; From the Harrison Department of Surgical Research, Schools of Medicine, University of Pennsylvania.

Arch Surg. 1938;36(3):500-508. doi:10.1001/archsurg.1938.01190210129008
Abstract

The rupture of abdominal wounds, with or without evisceration, is an old story. Even with the development of modern aseptic technic and a more intelligent handling of tissues, this complication continues to occur in from 1 to 3 per cent of all abdominal operations. Starr and Nason1 found it in 0.61 per cent of their cases after laparotomy. Fincke2 reported an incidence of 1.1 per cent; Meleney and Howes,3 of from 1 to 2 per cent, and Eliason and McLaughlin,4 of 0.27 per cent. Sokolov5 reported an incidence in Europe of from 2 to 3 per cent. That this complication occurred in wounds which were not infected, in which hemostasis was good, in which trauma to the tissues and tension were minimal and in which unusual strain was obviated suggested that additional factors of a general character might be playing a part in the disruption of certain abdominal wounds. The fact that the majority of these accidents occur after

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