Whatever may be the cause of migraine, I believe the consensus is that its mechanism resides in the cerebrum and probably in the cortical vessels. The almost consistent association of the headache with fortification figures, the occurrence of which usually is the prodromal or initial event in an attack, strongly suggests that the mechanism has its beginning about the calcarine fissure.
So far as I can ascertain, no pathologic condition of the visual cortex or other structures in the brain has been found which could unequivocably be pointed out as the exciting factor in migraine. Because I feel that such a condition can be demonstrated in the case to be described, I am presenting the following report.
REPORT OF CASE
L. I.,1 a white woman aged 30, was referred to me by Dr. C. M. Wray, of Iowa Falls, Iowa, in October 1936.
—The patient complained of
HYNDMAN OR. MIGRAINE CAUSED BY DEMONSTRABLE PATHOLOGIC CONDITIONSREPORT OF A CASE WITH CURE BY REMOVAL OF SMALL TUMOR IN CALCARINE FISSURE. Arch Surg. 1939;39(1):104-107. doi:10.1001/archsurg.1939.01200130107008