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December 1939


Author Affiliations

From the Section on Anesthesia, the Mayo Clinic.

Arch Surg. 1939;39(6):1001-1005. doi:10.1001/archsurg.1939.01200180102009

This paper concerns some of the important features of anesthesia induced by various gases from the standpoint of preoperative medication, physiologic phenomena associated with administration of most inhalation anesthetic agents and supportive measures for the patient during anesthesia.

In order to allay fear and promote rest, it is customary to administer a sedative agent to most patients before the operation. Usually morphine sulfate is administered, because it promotes rest and diminishes the patient's perception of pain. Although as a rule opium derivatives do not produce sleep unless given in large doses, they do enhance the effect of most soporific drugs, such as bromides and barbiturates. For this reason it is common practice to use such agents as pentobarbital sodium, sodium amytal and various other barbiturates and bromide preparations in conjunction with opiates. The different drugs of the atropine series, such as belladonna, atropine sulfate and scopolamine, are used routinely to

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