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In experimental animals long bones have been lengthened abnormally by increment from epiphysial cartilages transplanted to their shafts from neighboring bones. The grafts in these experiments were total massive segments, thick layers of adjacent bone from the epiphyses and diaphyses being included with the cartilage. Clinical application of the procedure has been precluded by the magnitude of the operation and the uncertainty of results.
In the experiments described here the possibility of lengthening bone by a less formidable procedure was investigated. All attempts, however, were unsuccessful.
In each of 8 goats approximately 1 month old two segments of the epiphysial cartilage plate with the adjacent layers of bone were removed from opposite sides of the femur and transplanted to the shaft of the tibia. The two segments of cartilage removed constituted less than half the plate, the central portion being left undisturbed. These segments were inserted between the two
BISGARD JD. TRANSPLANTED EPIPHYSIAL CARTILAGE. Arch Surg. 1939;39(6):1028-1030. doi:10.1001/archsurg.1939.01200180129012