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Article
June 1942

ABSORPTION OF SURGICAL GUT (CATGUT)II. PEPSIN DIGESTION TESTS FOR EVALUATION OF DURATION OF TENSILE STRENGTH IN THE TISSUES

Author Affiliations

CHICAGO
From the Department of Surgery, the University of Chicago, the School of Medicine.

Arch Surg. 1942;44(6):984-1003. doi:10.1001/archsurg.1942.01210240023002
Abstract

The decline in tensile strength of various sizes, types and brands of surgical gut (catgut) in the tissues was reported in a previous communication.1 A considerable amount of variation was generally observed in the behavior of the different products studied. This report deals with digestion tests in pepsin and the relation of the digestion time in pepsin to the duration of tensile strength of catgut in the tissues.

Kraissl and Meleney2 reported an ingenious method of assaying the resistance of catgut by trypsin digestion in vitro. The end point, at which the catgut undergoes complete loss of tensile strength in the digestive solution, is recorded by means of an electric clock. The electric current to the clock is shut off by means of a switch which is thrown by a counterweight when the catgut strand breaks. The digestion time in hours can then be determined from the time

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