The significance of the hypoproteinemic state with regard to operation has been recognized only during the past few years. As a result, a considerable amount of investigation, experimental and clinical, has been carried out on the problems associated with the causation and the therapy of hypoproteinemia. These problems at first appeared to be simple, but with a greater understanding of the syndrome associated with hypoproteinemia came the realization that many questions still remain unanswered. Patients with hypoproteinemia exhibit puzzling variations in their responses to treatment. The problem is not merely one of protein replacement. It is our purpose here to present a classification of the various forms of hypoproteinemia, to examine the causative factors involved in various hypoproteinemic states and to describe the results of the transfusion of ascitic fluid in this group of patients.
Any classification is useful only so far as it tends to clarify the factual
DAVIS HA, GETZOFF PL. HYPOPROTEINEMIA IN SURGICAL DISEASESRELATION OF THE SERUM PROTEIN LEVEL TO HEPATIC FUNCTION AND THE INFLUENCE OF THE TRANSFUSION OF ASCITIC FLUID. Arch Surg. 1942;44(6):1071-1090. doi:10.1001/archsurg.1942.01210240110008