[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address Please contact the publisher to request reinstatement.
[Skip to Content Landing]
December 1942


Author Affiliations

From the May Institute for Medical Research, the Jewish Hospital.

Arch Surg. 1942;45(6):964-968. doi:10.1001/archsurg.1942.01220060103008

In view of the frequent association of varicose veins of the extremities with trophic changes in the skin, it becomes important to ascertain the state of the circulation in the former condition. Using the same patient, de Takáts and his associates1 compared the gaseous content of venous blood from a normal upper extremity with that from a lower extremity with varicose veins and found a uniform increase in carbon dioxide and a decrease in oxygen content in the sample obtained from the lower limb. A similar procedure in a group of normal subjects revealed no such difference, at least as far as carbon dioxide content was concerned. On the basis of these results, the authors concluded that the tissues of a leg with varicosities are in a state of chronic anoxemia. According to them, this factor together with the retention of carbon dioxide and other waste products is responsible

First Page Preview View Large
First page PDF preview
First page PDF preview