The present day treatment of burns, particularly their emergency handling in large numbers of cases under conditions encountered in warfare, leaves much to be desired.
This paper deals with the local treatment of second degree burns, in which by definition the epidermis is not completely destroyed but in which the lesion may involve all the superficial layers down to the stratum germinativum from which the mature epithelium originates. Third degree burns present another problem; obviously if the epidermis is completely destroyed, the wounds must heal by granulation or second intention and therefore probably require some form of grafting.
Most of the widely used methods of treating burns have as their object the formation of an eschar over the burned area beneath which healing and epithelization can take place. This eschar is usually produced by repeated application of solutions of various drugs or drug combinations with the common property of coagulating
ANDRUS WD, NICKEL WF, SCHMELKES FC. TREATMENT OF BURNS WITH CHEMOTHERAPEUTIC MEMBRANES. Arch Surg. 1943;46(1):1-8. doi:10.1001/archsurg.1943.01220070004001