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Article
March 1943

THE SOLID CARBON DIOXIDE-FERRIC CHLORIDE TECHNIC FOR HEMOSTASISEXPERIMENTAL STUDY OF ITS EFFECTIVENESS IN BRAIN, VISCERA AND SUPERIOR SAGITTAL SINUS

Author Affiliations

NEW YORK
From the Department of Neurology, Columhia University, College of Physicians and Surgeons, and the Neurological Institute of New York.

Arch Surg. 1943;46(3):386-394. doi:10.1001/archsurg.1943.01220090081006
Abstract

A new technic has been developed with experimental animals for the control of bleeding from the cross-sectional surfaces of vessels in the brain and the viscera, as encountered after excision of blocks of tissue, and from lacerations of the superior sagittal sinus. At this time this procedure may have special application in war surgery.

In a report on a new method of excising blocks of brain tissue with minimal bleeding by means of liquid nitrogen and a mechanical device, Koskoff and his associates1 stated: "The slight hemorrhage which usually follows the removal of the instrument is easily controlled by pouring a small amount of liquid nitrogen into the bleeding area. This congeals the blood and a dry crater remains." In an earlier paper2 I have discussed the effects of low temperature freezing on cerebral and vascular tissues. This type of refrigeration preserves cell structure; the tissues return to

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