Carcinoid tumors are rare, but, judging from the volume of literature concerning them, probably few lesions of equal obscurity have received the same degree of attention. Moreover, the relatively common appendical carcinoid tumor has been superseded in point of interest by a small group localized elsewhere in the gastrointestinal tract, notably in the ileum. There are many reasons why this small group has merited what many believe to be unwarranted attention. Whereas appendical carcinoid tumors are often symptomless, those involving the ileum produce clinical evidence of obstruction in about one third of the cases, and small tumors thus located may produce major disturbances. Appendical carcinoid tumors are usually single, whereas about 25 per cent of their ileal counterparts appear as multiple tumor nodules.
But perhaps the most interesting feature connected with the group as a whole concerns the question of malignancy. Carcinoid tumors were regarded originally as ordinary (although small)
DOCKERTY MB, ASHBURN FS. CARCINOID TUMORS (SO-CALLED) OF THE ILEUMREPORT OF THIRTEEN CASES IN WHICH THERE WAS METASTASIS. Arch Surg. 1943;47(3):221-246. doi:10.1001/archsurg.1943.01220150002001