In advocating a local treatment for burns, it is important to take into consideration the way in which the body attempts to seal off the burned areas. This is done by the transudation of a fluid containing plasma protein, and with the evaporation of the water present in this fluid, the protein is left as a protective covering. Petit,1 in 1915, was one of the first to follow this line of reasoning and suggested the use of horse serum in the treatment of burns and wounds; again, in 1929, Monteith and Clock2 described 5 cases of burns treated by this method. Shortell, Cotting and Leary,3 in 1917, first described the use of bovine serum for this purpose. Aside from these few reports there has been little investigation with this approach in mind until recently.
Due to the war it is now essential that we have an agent
CURTIS RM, BREWER JH. CASEIN IN THE LOCAL TREATMENT OF BURNS AND WOUNDS. Arch Surg. 1944;48(2):130-136. doi:10.1001/archsurg.1944.01230010135006