The purpose of this article is to present the results of experiments which were intended more to explore new avenues in the physiology of the lymph system than to give intensive study to individual aspects of a limited problem. At this writing it is uncertain when it will be possible to support by a longer series of experiments the conclusions obtained from relatively few pioneering observations.
It has long been known that ligation of the thoracic duct causes deposition of chyle in the retroperitoneal tissues. Whether this condition is due to a rupture of a lymph vessel1 or whether it represents a transudation through an intact vessel wall2 has never been decided. The first experiments were planned to shed light on this problem alone, but they soon presented other facets which invited exploration.
When the chyle-bearing thoracic duct of the cat is ligated in the chest according
LEE FC. PERMEABILITY OF LYMPH VESSELS AND LYMPH PRESSURE. Arch Surg. 1944;48(5):355-365. doi:10.1001/archsurg.1944.01230010366001