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Article
October 1944

INTRAVENOUS ADMINISTRATION OF DEXTROSE IN THE TREATMENT OF PATIENTS WITH DISEASE OF THE BILIARY TRACT

Author Affiliations

PHILADELPHIA; MEDICAL CORPS, ARMY OF THE UNITED STATES
From Surgical Service B, Hospital of the University of Pennsylvania and The Harrison Department of Surgical Research, University of Pennsylvania School of Medicine.

Arch Surg. 1944;49(4):238-240. doi:10.1001/archsurg.1944.01230020246005
Abstract

Determination of the glycogen and lipid content of samples of liver obtained from patients in the course of operations on the biliary tract indicated that the diet high in carbohydrate and protein advocated by us1 was more effective in decreasing the fat content of the liver than in elevating the glycogen content. The present study was undertaken to determine the effectiveness of intravenous administration of dextrose during the twelve hours preceding operation in increasing liver glycogen in patients with disease of the biliary tract.

The value of giving intravenous infusions of dextrose solution to patients with disease of the biliary tract in preparation for surgical treatment has at times been overemphasized. Nevertheless, when used as a supplement to a suitable diet and not as a substitute for diet they appear to be useful. Many of these patients show histologic evidence of hepatic damage at operation, and it seems of

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