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Article
July 1945

HEMODYNAMIC AND BIOCHEMICAL CHANGES IN DOGS SUBJECTED TO SECTION OF THE SPINAL CORDCHANGES IN DOGS SURVIVING OPERATION FOR PROTRACTED PERIODS

Author Affiliations

CHICAGO
From the Departments of Medicine, Biochemistry and Surgery, University of Chicago.

Arch Surg. 1945;51(1):42-50. doi:10.1001/archsurg.1945.01230040045006
Abstract

In a previous paper1 studies were reported of the physiologic and biochemical changes that occurred in dogs during the acute stage of low blood pressure following section of the spinal cord at the eighth cervical segment in order to determine their bearing on the syndrome of surgical shock. In that study two groups of animals were used. One group was given adequate care following section so that recovery and survival within the limits of the surgical procedures performed might be reasonably assured. Inasmuch as there is little detail in the literature concerning shifts of electrolytes and other biochemical shifts that occur during the recovery of animals from the state of low blood pressure and "spinal shock" following section of the cord, it was believed that further studies on this surviving group would provide useful data. Also, it was thought that the information obtained from these biochemical studies might have

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